The 12-year follow-up of survival, chronic adverse effects, and retention of arsenic in patients with acute promyelocytic leukemia

To the editor: Arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) have demonstrated notable success in the treatment of acute promyelocytic leukemia (APL).[1][1][⇓][2]-[3][3] However, few studies have reported the adverse effects (AEs), long-term toxicity, and secondary carcinogenesis of