Ultrasonically controlled-release target medicinal preparation and production method thereof

2009 
The invention discloses a biologically degradable ultrasonically controlled target granular medicinal preparation and a production method thereof. The ultrasonically controlled target granular medicinal preparations are 0.5-0.8 microns wide granules made from biologically degradable macromolecules and medicines; the granules are a) porous particulates with pore diameters of 10-1000nm or b) a hollow capsule. The ultrasonically controlled (passively guided) target medicinal release preparation can be transported into human blood cycle system or the diseased part of a human body through injectionor venous perfusion; ultrasonic transmission characteristic on part of a human body with preparation can be changed through the physical theory of ultrasonic waves to generate featured ultrasonic image, thereby increasing the contrasts degree between diseased part and normal tissue as well as between movable part and static part, and carrying out ultrasonic development; simultaneously, the irradiating energy of the ultrasonic waves can promote the release of medicine so as to control the release of medicine by ultrasonic waves.
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