Successful Bridge to Lung Transplantation with Transcatheter Aortic Valve Replacement.

End-stage lung disease and advanced cardiac conditions are frequently seen together and represent a clinical dilemma. Even though both issues may be amenable to surgical management, combining lung transplantation with surgical valve repair is rarely done and theoretically associated with increased morbidity and mortality risks, especially in elderly patients. Here, we describe 2 patients presenting with end-stage lung disease and significant aortic stenosis who were successfully bridged to lung transplantation via transcatheter aortic valve replacement. Patient one was a 66-year-old male who underwent a double lung transplant 56 days after transcatheter aortic valve replacement. Patient two was a 70-year-old male who underwent a single right lung transplant 103 days after transcatheter aortic valve replacement. Both had uneventful postoperative courses and are alive at the one year time point with excellent performance status. This report suggests that transcatheter aortic valve replacement may favorably impact lung transplant candidacy for patients with end-stage lung disease in the setting of severe aortic stenosis, likely representing a better alternative to concomitant aortic valve replacement and lung transplantation in elderly patients.