Synthesis of 3-[125I]-iodo-phencyclidine for biological studies
1990
After verification of the biological activity of 3-iodo-PCP by binding studies to the N-methyl D-aspartate gated channel, 3-[125I]iodo-PCP was prepared by reaction of sodium iodide with a triazene precursor. The radiochemical yield was optimized and after HPLC purification, 3-[125I]iodo-PCP was obtained with a high radiochemical purity.
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