Acute ischemia of the extremities in the puerperal period

: The development of pharmacotherapy implies great advantages for patients, at the same time it is, however, also the source of more frequent side-effects of drugs, which may result also from mutual interactions of commonly used drugs. The authors describe a case of ergotism which developed as a result of drug interaction between the ergot uterotonic Cornutamine and the marcolid antibiotic Erythromycin. This interaction could have seriously damaged the health of the young woman. At the same time the authors remind of the clinical picture of ergotism and the possible way of its treatment. In the Czechoslovak literature no report on this interaction was published during the past three years.