Late Breaking Abstract - Atypical clinical and radiological presentation of SARS-CoV-2 infection in the elderly

Objectives: We sought to evaluate the association between age and presentation of SARS-COV2 infection Methods: Clinical presentation and radiological data of all consecutive COVID19 patients admitted to our Hospital between 01-03-2020 and 30-04-2020 were analyzed SARS-CoV-2 positive patients were diagnosed by either swab test or bronchoalveolar lavage Patients without proved SARS-CoV-2 infection or without HRCT scan were excluded All HRCT were reviewed and classified according to RSNA Classification of SARS-CoV-2 pneumonia(l) Results: Over the study period, 179 patients met the inclusion criteria Mean age was 67 years (SD 15 1, range 19-96);55 8% (N= 100) were male Of them, 22 patients (12%) had atypical clinical presentation The more frequent atypical presentations were cardiovascular, including syncope (N= 5, 22%) and heart failure (N= 5, 22%) HRCT was Typical in 151 (84 4%) patients, Indeterminate in 14 (7 8%), Atypical in 12 (6 7%), and Negative in 2 (0 01%) Among elderly patients (>70 years old) accounting for 44% of the total population (N=80), HRTC was more frequently Atypical (11/80 patients, 13 75%) compared to younger patients (<70 year of age, 1/99 patients, 1%) (p-value= 0 001) Similarly, the clinical presentation was more frequently atypical in the elderly (19/80, 23%) compared to the younger (3/99, 3 0%) (p-value <0 0001) Conclusions: Our study demonstrated that SARS-CoV-2 infections in elderly can results in atypical clinical and radiological presentation, potentially leading to misdiagnosis and unrecognized cases (1)Simpson S, et al Radiology 2020 doi: 10 1148/ryct 2020200152