Research progress of the relationship between lysosome and chemotherapy resistance

Chemotherapy is widely used in the treatment of malignant tumors, but chemotherapy resistance seriously affects its effect. Meanwhile, chemotherapy resistance is one of the main reasons of treatment failure. Recently, researches show that lysosome, is the main site of eukaryotic cell protein degradation, plays an important role in tumor cell resistance to chemotherapy. This paper reviews the research progress of the relationship between lysosome and chemotherapy resistance. Key words: Lysosome; Neoplasms; chemotherapy resistance