A study on helicobacter pylori infections in patients with chronic obstructive pulmonary disease

Objective To investigate the association between helicobacter pylori and COPD,and the mechanism that Hp lead COPD. Methods Fifty-two patients with acute exacerbations of COPD, 35 patients with stable COPD and 22 healthy subjects were all tested for pulmonary function test, urea 13C breath test,and serum were measured C-reactie protein,WBC. Results There is no significantly difference between the positive rate of Hp in patients with acute exacerbations of COPD and that in stable COPD （ P 〉0.05） ,but the positive rates of Hp in patients with acute exacerbations of COPD and stable COPD, compared with healthy subjects,were significantly different （ P M0.01） acute exacerbations patients of COPD with Hp infection by serum C-reactie protein, white blood cells than the total number of non-Hp infection were significently higher （ P M0.01）. Conclusions Hp infection associated with COPD,and Hp infection may be a potential disease risk factors. Key words: Pulmonary disease,obstructive; Helicobacter pylori