Discovery of Novel Hydroxy Pyrazole Based Factor IXa Inhibitor.

Dange Vijaykumar,Paul A. Sprengeler,Michael Shaghafi,Jeffrey R. Spencer,Brad A. Katz,Christine Yu,Roopa Rai,Wendy B. Young,Brian E. Schultz,James W. Janc

Discovery of Novel Hydroxy Pyrazole Based Factor IXa Inhibitor.

2006

Dange Vijaykumar
Paul A. Sprengeler
Michael Shaghafi
Jeffrey R. Spencer
Brad A. Katz
Christine Yu
Roopa Rai
Wendy B. Young
Brian E. Schultz
James W. Janc

Synthesis and biological data of a novel selective and efficacious factor IXa inhibitor are described along with its crystal structure in factor VIIa.

Keywords:

Pyrazole
Factor IXa
Organic chemistry
Chemistry

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