2-methyl-4-amino-5-(substituted-1,2,3-triazolyl)methylpyridine derivatives having bactericidal activity, and preparation method and application thereof
2014
The invention discloses 2-methyl-4-amino-5-(substituted-1,2,3-triazolyl)methylpyridine derivatives having a bactericidal activity, and a preparation method and an application thereof, wherein the derivatives have the structural formula described in the specification, wherein R represents H or I, X represents O, NH or S, Y represents benzoylamide thiocarbonyl or substituted benzoylamide thiocarbonyl, 2-phenyl-1,3,4-thiadiazole(oxadiazole)-5-yl or 2-substituted phenyl-1,3,4-thiadiazole(oxadiazole)-5-yl, benzophenone (acetophenone) imine or substituted benzophenone (acetophenone) imine, and Y-involved substituents on a benzene ring mainly comprise H, halogen, nitro, cyano group, CF3, C1-4 alkyl, methoxyl, C1-2 carboxylic group or carboxylate group. The compounds have a significant control effect on wheat gibberellic hypha, rice rhizoctonia solani, cucumber borrytis cinerea, tomato alternaria solani, alternaria alternata and cucumber colletrichum orbiculare, and can be used for bactericidal active ingredients.
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