The assessment of significance of intermediate coronary stenosis with intravascular ultrasound

Objective:To compare the detection of stenosis by angiography and identified angiographic predictors of severe luminal stenosis on intravascular ultrasound(IVUS)in patients with intermediate coronary stenosis.Methods:150 coronary intermediate stenosis patients underwent quantitative coronary angiography(QCA) and IVUS assessment of the lesions artery.The results from IVUS and QCA were compared using unpaired t-test.Multiple regression analysis was performed to identify parameters that could predict the presence of severe stenosis on IVUS.Results:30%-50% stenotic coronary lesions were classified as intermediate by QCA.There was a right correlation between IVUS and QCA with respect to percentage of stenosis,minimum luminal diameter,reference segment diameter.In contrast,there was a difference in the assessment luminal diameter stenosis with luminal area stenosis.The lesions were detected by IVUS could find the severity of stenosis,could reduce much MACE relatively.Conclusions:In patients with angiographically intermediate lesions,the frequency of severe stenosis detected by IVUS was high,indicating that angiography underestimated the severity of stenosis.IVUS could be used to stratify these lesions into groups to avoid higher risk of MACE.