Trypsin inhibitory effect of wedelolactone and demethylwedelolactone

Samiulla D. Syed,Mundkinajeddu Deepak,Shivanna Yogisha,Arun P. Chandrashekar,Keerthi A. Muddarachappa,Prashanth D'Souza,Amit Agarwal,B. V. Venkataraman

Trypsin inhibitory effect of wedelolactone and demethylwedelolactone

2003

Samiulla D. Syed
Mundkinajeddu Deepak
Shivanna Yogisha
Arun P. Chandrashekar
Keerthi A. Muddarachappa
Prashanth D'Souza
Amit Agarwal
B. V. Venkataraman

Wedelolactone (WL) and demethylwedelolactone (DWL) isolated from Eclipta alba were tested in the trypsin inhibition bioassay (in vitro). Both compounds showed potent activity. IC50 values of WL and DWL were found to be 2.9 and 3.0 µg/mL respectively. Copyright © 2003 John Wiley & Sons, Ltd.

Keywords:

Enzyme
Botany
Biology
Biochemistry
Trypsin
Biological activity
IC50
Wedelolactone
Bioassay
Enzyme inhibitor
In vitro
Eclipta alba

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