Eczema Crónico das Mãos Relacionado com Alergia de Contacto a Lactonas Sesquiterpénicas e Partenolido

Allergic contact dermatitis to plants can assume different clinical patterns. We report a 63-year-old female patient with chronic hand dermatitis. Given the clinical suspicion of allergic contact dermatitis, patch tests were performed with the Baseline series of the GPEDC and a plants series which showed positivity to sesquiterpene lactone mix 0.1% pet (++) and parthenolide 0.1% pet (++) at day D2 and D4. These test results allowed the diagnosis of contact allergy to parthenolide that was related to occupational exposure Chamaemelum fuscatum during gardening. We emphasize the importance of a meticulous clinical history to increase the level of suspicion of Allergic contact dermatitis and evaluate the relevance of a positive patch test to sesquiterpene lactone and parthenolide as the etiology in chronic hand dermatitis.