Gastro-electric dysrhythm and lack of gastric interstitial cells of cajal

The pathophysiology underlying gastrointestinalcomplications of long-standing diabetes is poorly understood.Recent evidence suggests an important role of intestitialcells of cajal in controlling gastrointestinal motility. The aimof this study was to clarify the changes of ultrastructuralcharacteristics of interstitial cells of cajal in stomach ofdiabetic gastro-electric dysrhythmic rats.