P779 Pre-exposure prophylaxis use among trans and gender diverse people: characteristics and behaviour from the EPIC-NSW trial

Background Trans and gender diverse (TGD) individuals are at higher risk of HIV than the general population. TGD individuals are under-represented among HIV pre-exposure prophylaxis (PrEP) users, hence little is known about their pill-taking behaviours. We describe demographic characteristics and PrEP adherence by TGD individuals in the EPIC-NSW study. Methods From March 2016 to April 2018, 9,708 individuals were enrolled in EPIC-NSW. At baseline, then quarterly, participants were invited to complete an optional online behavioural and adherence survey. Factors previously associated with lower PrEP adherence were compared between TGD and non-TGD participants using chi-squared tests. Results Of the 6,942 EPIC-NSW participants that completed any survey, 96 identified as TGD (1.4%), including 38 trans women and 15 trans men. TGD participants were significantly younger than non-TGD individuals (mean 34 vs 39 years, p Conclusion Despite increased levels of HIV-risk and socio-economic disadvantage, TGD participants had comparable levels of adherence to non-TGD EPIC-NSW participants. Additional services for TGD including counselling and PrEP monitoring within a supportive environment may be warranted to ensure ongoing protection against HIV. Disclosure No significant relationships.