RESEARCH PROGRESS OF TISSUE ENGINEERING TECHNIQUE IN ESOPHAGEAL DEFECT REPAIR AND RECONSTRUCTION

OBJECTIVE: To review the research progress of the tissue engineering technique in the esophageal defect repair and reconstruction. METHODS: The recently published clinical and experimental literature at home and abroad on the scaffold materials and the seeding cells used in the tissue engineered esophageal reconstruction was consulted and summarized. RESULTS: A large number of basic researches and clinical applications show that the effect of the tissue engineered esophagus is close to the autologous structure and function of the esophagus and it could be used for the repair of the esophageal defect. However, those techniques have a long distance from the clinical application and need an acknowledged rule of technology. CONCLUSION: Tissue engineering technique could provide an innovative theory for the esophageal defect reconstruction, but its clinical application need further research.