Preparation of Ferrocene Functionalized Graphene Modified Electrode and Its Application in Detection of Dopamine

A complex of ferrocene functionalized graphene oxide( Fc / GO) was prepared through FriedelCrafts acylation method and characterized by tunable electron microscopy( TEM),Fourier transform infrared spectroscopy( FTIR) and X-ray diffraction( XRD). The Fc / GO complex was immobilized on glassy carbon electrode( GCE) with Nafion,and electrochemically reduced by potentiostatic reduction method to get Fc /ERGO / GCE. The results showed that the obtained Fc / ERGO / GCE had good catalytic performance for the oxidation-reduction of dopamine( DA). A pair of peaks near 0. 2 V in the cyclic voltammogram attributed to DA was observed. The differential pulse voltammetric( DPV) peak current was proportional to the concentration of DA in the range from 0. 4 μmol / L to 300 μmol / L( R2= 0. 9998),with a limit of detection of0. 08 μmol / L. The recoveries of DA in the spiked human urine samples were 92. 5%-105. 0% with relative standard derivations( RSDs) of less than 5%( n = 5),which indicated that the fabricated Fc / ERGO / GCE was suitable for the determination of dopamine in real samples.