Cerebral Endothelial Regeneration Following Brain Injury

It has not been determined when and in which area regeneration of the cerebral endothelium occurs after brain injury (Orita et al. 1988). We therefore studied bromodeoxyuridine (BrdU) uptake by regenerating endothelial cells in two different groups of rats given cold lesions using immunohistochemistry employing anti-BrdU monoclonal antibody, anti-factor VIII-related antigen antibody and anti-glial fibrillary acidic protein antibody.