Molecular analysis of the gut microbiota of identical twins with Crohn's disease

Molecular analysis of the gut microbiota of identical twins with Crohn’s disease Johan Dicksved 1* , Jonas Halfvarson 2* , Magnus Rosenquist 1 , Gunnar Jarnerot 2 , Curt Tysk 2,5 , Juha Apajalahti 3 , Lars Engstrand 4 , and Janet K. Jansson 1,6 *Authors contributed equally to this work Swedish University of Agricultural Sciences, Department of Microbiology, Uppsala, Sweden Division of Gastroenterology, Department of Medicine, Orebro University Hospital, Orebro, Sweden. Alimetrics Ltd, Hoylaamotie 14, 00380 Helsinki, Finland Swedish Institute for Infectious Disease Control, Department of Bacteriology, Solna, Sweden School of Health and Medical Sciences, Orebro University, Orebro, Sweden. Lawrence Berkeley National Laboratory, Division of Earth Sciences, 1 Cyclotron Rd., Berkeley, CA 94720 Keywords, Crohn’s disease, terminal-restriction fragment length polymorphism (T-RFLP), discordant twins, concordant twins, Bacteroides Running title. Twin study of Crohn’s disease