Comparison of two glycemic discharge goals in ED patients with hyperglycemia, a randomized trial

Abstract Study objective Hyperglycemia is commonly encountered in the ED; the importance of glucose reduction in patients well enough to be discharged is unknown. Methods We conducted a prospective, randomized trial of ED patients with hyperglycemia with a glucose value 400–600 mg/dL who were discharged from the ED, excluding those with type 1 diabetes mellitus. Patients were randomly assigned to a discharge glucose goal, Results Among 110 enrolled patients, 57 were assigned to moderate and 53 to loose glycemic control. Median (IQR) length of stay was 211 min (177–288 min) for the moderate group and 216 min (151–269 min) for the loose group (difference, 17 min [95% CI −15 to 49 min]). ED length of stay for those with an actual discharge glucose Conclusion In the intention-to-treat analysis, ED length of stay and 7-day outcomes were not significantly different whether moderate or loose glycemic control was pursued. However, the length of stay for those with discharge glucose Trial Registration: Clinicaltrials.gov NCT02478190