Research progress on anti-cerebral ischemia drugs targeting anti-inflammatory factors

2012 
In recent years,the inflammatory reaction of cerebral ischemia has attracted more and more attention of the scholars.Inflammation is one of the important pathophysiological mechanisms of ischemic brain damage,which is involved in the occurrence and development of ischemic stroke and relative with life-threatening complication accompanying ischemic stroke.Additionally,inflammatory factors produced by cerebral ischemia constitute the basis of ischemic injury.This review summarizes the latest research development of some kinds of inflammatory factors related to cerebral ischemia and IL-1,IL-8,IL-10,ICAM-1,TNF-alpha and MC4 as a target for anti-cerebral ischemic drug.
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