Abstract 11250: Bone Marrow Mononuclear Cell Transplantation Improves Cardiac Function in Ischemic Cardiomyopathy via High Mobility Group Box 1 Released from Dead Donor Cells

Masahiro Kaneko,Yasunori Shintani,Takuya Narita,Chiho Ikebe,Niall G. Campbell,Vinit Sawhney,Nobuko Tano,Steven R. Coppen,Kenta Yashiro,Ken Suzuki

Abstract 11250: Bone Marrow Mononuclear Cell Transplantation Improves Cardiac Function in Ischemic Cardiomyopathy via High Mobility Group Box 1 Released from Dead Donor Cells

2012

Masahiro Kaneko
Yasunori Shintani
Takuya Narita
Chiho Ikebe
Niall G. Campbell
Vinit Sawhney
Nobuko Tano
Steven R. Coppen
Kenta Yashiro
Ken Suzuki

Injection of bone marrow mononuclear cells (BMCs) improves cardiac function in ischemic cardiomyopathy allegedly due to the “paracrine effect” mediated by secretion from surviving BMCs. However, do...

Keywords:

Stem-cell therapy
Cardiology
Cardiac function curve
Internal medicine
Bone marrow
Ischemic cardiomyopathy
Paracrine signalling
Inflammation
Heart failure
Transplantation
Medicine

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