Sympathetic sudomotor and vasoconstrictive neural function in patients with Parkinson's disease

Abstract To evaluate sympathetic sudomotor and vasoconstrictive neural function in Parkinson's disease (PD), we simultaneously recorded sympathetic skin response (SSR) and skin blood flow (SVR; skin vasomotor reflex), as well as skin sympathetic nerve activity (SSNA) measured in peroneal nerves by microneurography, comparing 12 patients with idiopathic PD with 16 healthy controls. Resting SSNA frequency (8.8 ± 4.3 bursts/min) was significantly lower in PD patients than in controls ( p p