Detecting method of blood-retinal barrier.

The retinal neuronal survival is closely correlated with healthy circulation of blood in the retina.In hypoxic-ischemic conditions,neuronal survival is not only influenced by its own peculiarity,but also regulated by its microenvironment.The blood-retinal barrier(BRB) plays an important role in the homeostatic regulation of the microenvironment in the retina.It is greatly important to understand the detecting method of blood-retinal barrier for research on blood-retinal barrier breakdown in hypoxic-ischemic retinopathy.This review introduced several kinds of methods of detecting blood-retinal barrier,so as to provide methodological data for investigator to detect blood-retinal barrier breakdown.