P-Glycoprotein Influence on the Brain Uptake of a 5-HT2A Ligand: [18F]MH.MZ

Ulrich Schmitt,Dianne E. Lee,Matthias M. Herth,Markus Piel,Hans Georg Buchholz,Frank Roesch,Christoph Hiemke,Hartmut Lueddens,Fabian Debus

P-Glycoprotein Influence on the Brain Uptake of a 5-HT2A Ligand: [18F]MH.MZ

2011

Ulrich Schmitt
Dianne E. Lee
Matthias M. Herth
Markus Piel
Hans Georg Buchholz
Frank Roesch
Christoph Hiemke
Hartmut Lueddens
Fabian Debus

Background/Aims: The serotonergic system, especially the 5-HT2A receptor, is involved in various diseases and conditions. We have recently developed a new [18F

Keywords:

Internal medicine
Endocrinology
Chemical structure
P-glycoprotein
Neuroscience
Blood–brain barrier
Serotonergic
Molecular biology
Receptor
Ligand
Biology
Pharmacokinetics
brain uptake

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