Human Pulmonary Hyperpolarized $^{129}$Xe MRI: a Preliminary Study

We study the feasibility and safety of human lung hyperpolarized (HP) 129 Xe magnetic resonance imaging (MRI). There is no significant change in physiological parameters before and after the examinations of all subjects. Compared with computed tomography, HP 129 Xe MRI is sensitive to earlier and smaller ventilation defects. The distribution of the HP 129 Xe MRI signal reflects the pulmonary compliance with the gravity gradient. This is the first application of HP 129 Xe MRI ventilation imaging in China, and this technology is expected to provide more useful information for clinical practice.