Acquired resistance to temsirolimus in human renal cell carcinoma cells is mediated by the constitutive activation of signal transduction pathways through mTORC2.

Ken-ichi Harada,Hideaki Miyake,Masafumi Kumano,Masato Fujisawa

Acquired resistance to temsirolimus in human renal cell carcinoma cells is mediated by the constitutive activation of signal transduction pathways through mTORC2.

2013

Ken-ichi Harada
Hideaki Miyake
Masafumi Kumano
Masato Fujisawa

Acquired resistance to temsirolimus in human renal cell carcinoma cells is mediated by the constitutive activation of signal transduction pathways through mTORC2

Keywords:

Sirolimus
Immunology
Phosphorylation
mTORC2
Pathology
Temsirolimus
TOR Serine-Threonine Kinases
Signal transduction
Apoptosis
Cancer research
Biology
Proto-Oncogene Proteins c-akt
Renal cell carcinoma

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