Progress on Biomarker of Alzheimer Disease

Biochemical markes proposed for Alzheimer disease (AD) are based on pathophysiologic processes such as amyloid plaque formation,inflammation,oixdative stress,lipid metabolism,and vascular disease.Most proteins examined in plasma or serum are biological cor- relations of AD.which may be helpful for diagnosis or therapy of AD.This paper reviews the progress on biomarker expression of AD and its value in clinical application.