α-Adrenergic Control of TSH Secretion in Man

It is well known that TSH secretion is under the control of different factors (1). On thyrotrophs, there is a direct negative control exerted by thyroid hormones and dopamine, while TRH released by hypothalamic neurons has a stimulatory effect on TSH secretion. These neurons are probably under the positive control of the noradrenergic system (1,2).