Outcomes following liver transplantation in young infants: Data from the SPLIT registry.

Liver transplantation (LT) in young patients is being performed with greater frequency. We hypothesized that objective analysis of pre, intra and post-operative events would help understand contributors to successful outcomes and guide transplant decision processes. We queried SPLIT registry for pediatric transplants between 2011 and 2018. Outcomes were compared for age groups: 0- 10 kg. 1033 patients were available for analysis. Cholestatic disease and fulminant failure was highest in group A and those =40, post-operative hospital stays, rejection and non-anastomotic biliary strictures were highest in group A with lowest survival at 93.1%. Infants 0 to <3-month and those <5 kg need more intensive care with lower survival and higher complications. Importantly, potential LT before reaching Status 1a/1b and aggressive post-operative management may positively influence their outcomes.