Abstract WP543: Apelin Impairs Endothelium-Derived Hyperpolarizing Factor (EDHF)-Induced Relaxation of Cerebral Arteries by Inhibiting Activation of Large Conductance, Calcium-Activated K (BK Ca ) Channels in Vascular Smooth Muscle

Stephen T. O’Rourke,Amreen Mughal,Chengwen Sun

Abstract WP543: Apelin Impairs Endothelium-Derived Hyperpolarizing Factor (EDHF)-Induced Relaxation of Cerebral Arteries by Inhibiting Activation of Large Conductance, Calcium-Activated K (BK Ca ) Channels in Vascular Smooth Muscle

2019

Stephen T. O’Rourke
Amreen Mughal
Chengwen Sun

Introduction: Apelin is a peptide found in fat cells, endothelial cells and CNS neurons. Apelin levels are increased in conditions linked to cardiovascular disease (e.g. obesity, diabetes). Apelin ...

Keywords:

Vascular smooth muscle
Cerebral arteries
Physical therapy
Calcium
Apelin
Endocrinology
Endothelium-derived hyperpolarizing factor
Conductance
Medicine
Diabetes mellitus
Internal medicine
ca channel

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