Type 2 Diabetic Nephropathy:An Analysis of 210 Cases

Objective To explore the related etiology of type 2 diabetic nephropathy(DN)by observing the DN urinary albumin excretionrate(UAER)in different treatments of the disease.Methods Total 210 cases of DN were randomly divided into three groups(70 cases foreach group)according to two-time consecutive measured UAER.Group A,conventional treatment group,was given nitrendipine antihypertensive therapy,Group B was given insulin therapy for three months after oral administration of nitrendipine,and Group C was given insulin therapy.The patients of the three groups were given diabetes diet therapy,without any low-salt diet.The UAER was detected and recorded threetimes within 8 months.Results There was a significant difference in the UAER value of Group B after six months compared with its own initial value,and in the UAER values of Group C after six months and eight months compared with its own initial value(P0.05).There was asignificant difference in the UAER value of Group C after six months and in the values of Groups B and C after eight months compared withtheir own initial values(P0.05).Conclusion DN is one of the most common and severe chronic complications of diabetes and play an important role in the occurrence and development of diabetes microvascular complications.The early use of insulin therapy for diabetes can effectively delay the occurrence of DN.