Dopamina — aspekty patofizjologiczne i kliniczne

This article summarizes the recent views on the role of dopamine in the pathophysiology of essential hypertension, experimental hypertension and pheochromocytoma. The studies on antiproliferative action of dopamine on VSMC (vascular smooth muscle cell) are mentioned. The authors discuss the potential role of dopamine and its metabolites as a marker of malignant hypertension and paraganglioma, especially in patients with SDHB (succinate dehydrogenase complex subunit B) gene mutations. The clinical implication of specific D1 agonist fenoldopam is also discussed. Arterial Hypertension 2011, vol. 15, no 1, pages 37–41