Application of molecularly-imprinted polymers in solid-phase microextraction techniques

Abstract In spite of the huge developments in analytical instrumentation during the past two decades, sample preparation is still considered as the most critical step in the whole analytical process. It is required in order to remove interferences and preconcentrate target analytes. Efforts have been made to improve selectivity during extraction. Molecularly-imprinted polymers (MIPs) have affinity for the original template molecule and have been used in applications, such as chemical separation, selective extraction, catalysis, or molecular sensing. In the present review, we describe the application of MIPs in the various modes of solid-phase microextraction.