Abstract 18356: The Breast Cancer Resistance Protein (BCRP) c.421C>A Single Nucleotide Polymorphism Increases Steady-state Plasma Concentration of Rosuvastatin

Background: The hepatic efflux transporter BCRP (ABCG2) c.421C>A (p.Gln141Lys) single nucleotide polymorphism (SNP) has previously been shown to increase the cholesterol-lowering efficacy of rosuva...