Creutzfeldt-Jacob disease.

Background: A 57-year-old female with a past medical history of breast carcinoma presented with symptoms of anxiety, concentration difficulties, personality changes and vertigo. Routine laboratory examination and CT scan of the brain were unremarkable. The initial treatment with antidepressiva was unsuccessful and the patient developed a rapidly progressive dementia and cerebellar ataxia. Two months after the onset of the initial symptoms, the patient was hospitalized with an acute confusional state and myoclonic jerks.