One-Pot Synthesis of Benzo[1,4]thiazin-3(4H)-ones and a Theoretical Study of the S–N Type Smiles Rearrangement Mechanism

Benzo[1,4]thiazin-3(4H)-one derivatives are conveniently prepared in one pot via a Smiles rearrangement (SR) tandem reaction. In order to understand the reaction, we present here a theoretical study on the S–N type SR mechanism.