Localized Amyloidosis Of The Upper Respiratory System: Our Experience Of Three Cases And Review Of Article

Objective: To discuss the presentation, evaluation and the treatment options of localized amyloidosis affecting the upper respiratory system. Patients and Method: We conducted a retrospective study with analysis of amyloidosis by histopathologic investigations. We present three cases of localized amyloidosis; nasopharyngeal, oropharyngeal and laryngeal, with the review of literature. Results: Localized amyloidosis of the upper respiratory tract is a rare condition. The cases presented were diagnosed by histopathologic investigations. All of them were found to be free of systemic disease. They treated by surgical excision. The follow-up period ranged from two to five years. They are still being observed periodically. Conclusion: Histopathologic investigation is the gold standard for diagnosis. Simple surgical excision is the treatment for localized amyloidosis. Long term monitoring for local recurrences or subsequent development of systemic disease is mandatory. The work was done in Bakirkoy Dr. Sadi Konuk Education and Research Hospital.