Heart rate reduction by ivabradine reduces diastolic dysfunction and cardiac fibrosis.

David Busseuil,Yanfen Shi,Mélanie Mecteau,Geneviève Brand,Marc-Antoine Gillis,Eric Thorin,Caroline Asselin,Philippe Romeo,Tack Ki Leung,Jean-Gilles Latour,Christine Des Rosiers,Muriel Bouly,Eric Rhéaume,Jean-Claude Tardif

Heart rate reduction by ivabradine reduces diastolic dysfunction and cardiac fibrosis.

2010

David Busseuil
Yanfen Shi
Mélanie Mecteau
Geneviève Brand
Marc-Antoine Gillis
Eric Thorin
Caroline Asselin
Philippe Romeo
Tack Ki Leung
Jean-Gilles Latour
Christine Des Rosiers
Muriel Bouly
Eric Rhéaume
Jean-Claude Tardif

Objectives: To determine if heart rate (HR) reduction with ivabradine (IVA), a selective inhibitor of the pacemaker I f current, prevents cardiac dysfun

Keywords:

Heart rate
Cardiac fibrosis
Angiotensin II
Ivabradine
Cardiology
Diabetes mellitus
Internal medicine
Diastolic function
Diastole
Diastolic heart failure
Medicine

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