A phase II study of dovitinib in patients with recurrent or metastatic adenoid cystic carcinoma (ACC).

Patrick M. Dillon,Gina R. Petroni,Chris Moskaluk,Paula M. Fracasso,Michael G. Douvas,Jose-Ricardo Perez,Nikole Varhegyi,Snjezana Zaja-Milatovic,Christopher Y. Thomas

A phase II study of dovitinib in patients with recurrent or metastatic adenoid cystic carcinoma (ACC).

2015

Patrick M. Dillon
Gina R. Petroni
Chris Moskaluk
Paula M. Fracasso
Michael G. Douvas
Jose-Ricardo Perez
Nikole Varhegyi
Snjezana Zaja-Milatovic
Christopher Y. Thomas

e17092 Background: ACCs frequently acquire a chromosome (6:9) translocation that leads to overexpression of the MYB oncogene with autocrine activation of the fibroblast growth factor receptor (FGFR...

Keywords:

Adenoid cystic carcinoma
Pathology
Oncology
Phases of clinical research
Medicine
Internal medicine
Chromosomal translocation
Oncogene
Autocrine signalling
Fibroblast growth factor receptor
MYB
Chromosome

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