Effect of Preoperative Anxiety on Early Prognosis of Patients after Thoracoscopic Lung Cancer Resection

: 【中文题目：术前焦虑对胸腔镜肺癌根治术后患者 早期预后的影响】 【中文摘要：背景与目的 肺癌患者常伴焦虑，影响术后恢复。本研究旨在观察术前焦虑对胸腔镜肺癌根治术后患者早期预后的影响。方法 以胸腔镜肺癌根治术患者100例为研究对象，术前采用医院焦虑抑郁量表（hospital anxiety and depression scale, HADS）对患者进行评估，其中焦虑患者44例（焦虑评分≥8分）纳入焦虑组；非焦虑患者56例（焦虑评分 8) and 56 in control group (anxiety score<8). The primary endpoint: length of postoperative hospital stay. The secondary endpoint: length of hospital stay, visual analogue scale (VAS), the incidence of nausea and vomiting as well as postoperative new arrhythmia and the consumption of postoperative analgesic and rescue antiemetic. RESULTS: Compared with the control group, the length of postoperative hospital stay and hospital stay in the anxiety group were both significantly longer [(5.1±2.5) d vs (4.0±1.3) d, P<0.01; (10.9±4.0) d vs (9.1±4.1) d, P<0.05)], the VAS score and the incidence of nausea as well as arrhythmia were significantly increased [(4.7±1.9) vs (2.6±1.8), P<0.001; 40.9% vs 16.1%, P<0.01; 36.4% vs 20.7%, P<0.05], and the consumption of postoperative analgesic and rescue antiemetic were also significantly increased [(72.5±8.9) mL vs (68.2±9.4) mL, P<0.05; (2.1±2.9) mg vs (0.9±1.9) mg, P<0.05]. CONCLUSIONS: Preoperative anxiety can affect the early prognosis of patients after thoracoscopic lung cancer resection, prolong hospitalization time, increase the postoperative pain score and the incidence of postoperative nausea and new arrhythmia as well as the consumption of postoperative analgesic and rescue antiemetic.