Disseminated verrucous porokeratosis successfully treated with 5-FU followed by oral isotretinoin- a case report

Introduction Multiple clinical variants of porokeratosis are known The verrucous variant is usually confined to the buttocks porokeratosis ptychotropica and is one of the less commonly reported entities Case description We report a case of disseminated verrucous porokeratosis involving almost any area of the body mostly the upper trunk successfully treated with oral retinoids following topical FU Discussion Histological examination is crucial for the diagnosis The observation of multiple cornoid lamellae and the absence of other characteristic findings establish the diagnosis Several therapeutic modalities have been described therefore the approach to treatment must be individualized Our case adds to the growing list of porokeratosis rsquo variants and suggests that oral retinoids following topical FU is a good therapeutic alternative in the treatment of the disease nbsp