Studies on the role of viruses, bacteria, and M. pneumoniae as causes of lower respiratory tract infections in children.

The etiological roles of bacteria, viruses, and mycoplasmas were assessed simultaneously in 2 different populations of children from the same geographic area. These patients, some from a typical private practice in a small town and others from a rural environment, represent groups that have not been studied extensively. The significance of the agents varied between the groups in terms of frequency, character of associated illness, and age of patients involved. The data indicate the need for long-term observations in differing epidemiological settings to provide a rational basis for prophylaxis, diagnosis, and therapy of acute respiratory diseases.