Spanish Breast Cancer Research Group (GEICAM) population-based study on breast cancer outcomes (El Álamo project): Analysis of operable, node negative breast cancer patients

6044 Background: El Alamo project is a retrospective analysis of 15381 patients (pts) diagnosed of breast cancer (BC) across 43 of the main Spanish hospitals. Methods: Two cohorts were analysed: Alamo I (AI) consisted of 4532 pts diagnosed with BC between 1990 and 1993; Alamo II (AII) consisted of 10849 pts diagnosed between 1994 and 1999. AI and AII data were collected by end of year (yr) 2000 and 2003, respectively. 158 items per pt were recorded, including demographic, therapeutic and outcome data. Pts with operable node negative (NN) disease were selected. Results: In AI project, 48% (n=1806) of all pts presented with NN disease, vs. 54.4% in AII (n=4764). Median age at diagnosis was 58 yr (AI) vs. 59 yr (AII); 67.4% vs. 69.6% of pts were postmenopausal. T1 percentage increased from 47.6% (AI) to 57.4% (AII). Regarding treatment, 94% of pts in AII received adjuvant therapy (AT) vs. 86.3% in AI. AT in AI group were: chemotherapy (CT) (37.4%), hormone therapy (HT) (50.4%) and radiotherapy (RT) (32.4%). ...