Association between promoter hypermethylation of APC, CDH13, MLH1 and MGMT genes and colorectal cancer metastasis.

Oleg Ivanovich Kit,Dmitry I. Vodolazhsky,Konstantin Vladimirovich Dvadnenko,Elena N. Oleynikova,Denis D. Oleynikov,Olga A. Bogomolova,Irina V. Mezhevova,Denis S. Kutilin,Natalya N. Timoshkina,Yaroslav S. Enin,Irina I. Efimova,Anton Pushkin

Association between promoter hypermethylation of APC, CDH13, MLH1 and MGMT genes and colorectal cancer metastasis.

2016

Oleg Ivanovich Kit
Dmitry I. Vodolazhsky
Konstantin Vladimirovich Dvadnenko
Elena N. Oleynikova
Denis D. Oleynikov
Olga A. Bogomolova
Irina V. Mezhevova
Denis S. Kutilin
Natalya N. Timoshkina
Yaroslav S. Enin
Irina I. Efimova
Anton Pushkin

e15066Background: Aberrant methylation of CpG sites within promoter regions of cancer-related genes is an important epigenetic event in carcinogenesis. The frequency of methylation changes of diffe...

Keywords:

Pathology
DNA methylation
Gene
Colorectal cancer
Metastasis
Cancer research
MLH1
Medicine
CpG site
Methylation
Epigenetics
Carcinogenesis

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