'Pink eye' or 'zere oogjes' or keratoconjunctivitis infectiosa ovis (KIO). Clinical efficacy of a number of antimicrobial therapies.

Summary In a comparative study the clinical efficacy of five different treatments of keratoconjunctivitis infectiosa ovis (KIO) were tested, namely an intramuscular injection of chloramphenicol base (dosage 15 mg/kg), spiramycin base (Suanovil® dosages 10 to 25 mg/kg), oxytetracycline (Engemycine® Forte, Terramycin® LA, dosages respectively 5 and 10 mg/kg), tiamulin (Dynamutulin®, dosage 10 mg/kg) and subcutaneous injection of procaine penicillin G, benzathine penicillin G, and dihydrostreptomycin in the lower eyelid. It appeared from these field trials that spiramycin base, oxytetracycline and tiamulin had a clearly positive effect on the clinical course of ‘pink eye’, although with tiamulin there was only a temporary effect (high percentage of relapses). In view of the field data the following dosage schemes are, for the time being, advised: spiramycin. base (Suanovil®), and oxytetracycline (formulation with a good biological availability) both 20 to 30 mg/kg and, if necessary, to be repeated on days 5 ...