Effect of miRNA on biological characteristics of tumor
2008
Studies indicate that miRNAs correlate closely with tumorigenesis and tumor biological be-haviors, and play a significant role as a kind of regnlating factor in tumorigenesis, tumor cells proliferation, dif-ferentiation, apoptosis, invasion and metastasis, as well as in drug resistance of tumors. Further study of the targets and mechanisms of miRNA may be helpful to recognize the characterization of tumor biology and etiolo-gy, and bring new strategies for tumor therapy.
Key words:
MicroRNAs; Neoplasms; Gene expression regulation; Neoplastic processes; Drug resist-ance, neoplasm
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