Circumference-Based Criteria for Detection of Secondary Arm Lymphedema for Chinese Women

Abstract Background: Detection of upper limb lymphedema following treatment for breast cancer typically relies on interlimb circumference-based differences. Normative-determined criteria from an Australian population have high sensitivity and specificity for detection of mild lymphedema in Australian women. It is unknown whether these criteria are applicable to Chinese women whose body habitus is different from Australian women. The aims of this study, therefore, were to determine the normative-based interlimb circumference and volume differences in a Chinese population and whether specific population-based thresholds are required. Methods and Results: Arm circumferences at the wrist and at 10 cm intervals proximally to 40 cm were measured on both the dominant and nondominant limb in 484 healthy women, aged ≥20 years. Absolute interlimb differences and interlimb ratios were determined for the circumferences and derived 10 cm volume segments. Analysis of variance determined if the differences varied, depen...