Dissociation of FK506 Binding Protein 12.6 from Ryanodine Receptor Type 2 Is Regulated by cADPR but not β-Adrenergic Stimulation in Mouse Cardiomyocytes

Xu,Zhang,Zheng,Chen,Wei,Lin,Miao,Guangju,Ji,datun,Beijing

Dissociation of FK506 Binding Protein 12.6 from Ryanodine Receptor Type 2 Is Regulated by cADPR but not β-Adrenergic Stimulation in Mouse Cardiomyocytes

2009

Xu
Zhang
Zheng
Chen
Wei
Lin
Miao
Guangju
Ji
datun
Beijing

AIMS: β-adrenergic augmentation of Ca2+ sparks and cardiac contractility has been functionally linked to phosphorylation-dependent dissociation of FK506 binding protein 12.6

Keywords:

Stimulation
Contractility
FKBP
Molecular biology
Internal medicine
Adrenergic
Ryanodine receptor
Endocrinology
Chemistry
β adrenergic stimulation

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