Stereoselective Diels—Alder Reactions Promoted under Continuous-Flow Conditions by Silica-Supported Chiral Organocatalysts
2014
A simple HPLC column filled with silica-supported MacMillian catalyst works as a catalytic reactor for the Diels—Alder reaction between cyclopentadiene and cinnamic aldehyde affording the cycloadducts in high yields and enantioselectivities.
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